New publication: WHO catalogue of M. tuberculosis resistance mutations
The World Health Organization published its first catalogue of mutations in M. tuberculosis known to be associated with resistance to a range
Read in the Economist about CRyPTIC
Hot on the heels of the press release, the Economist have published an article describing the work of the CRyPTIC project. Note
Interview on the BBC World Service
You can hear the CRyPTIC Principal Investigator, Prof Derrick Crook, talking about the project and its impact on tuberculosis on News Hour
New logo celebrating the release of the CRyPTIC papers
To celebrate the release of the CRyPTIC dataset and the nine manuscripts deposited in preprint servers, we've made a new CRyPTIC logo
Press release – Largest ever global study of tuberculosis identifies genetic causes of drug resistance
Using cutting-edge genomic sequencing techniques, researchers at the University of Oxford have identified almost all the genomic variation that gives people resistance
New publication: Structure of MmpL3 protein
Oliver Adams, as part of his DPhil studies in Simon Newstead's group at the University of Oxford, has resolved the structure of
WHO tuberculosis mutation catalogue released
Last Friday 25 June 2021, the World Health Organization released their first report containing a catalogue of mutations in Mycobacterium tuberculosis and
Internal project seminars in June 2021
The analysis group will be presenting five consecutive seminars starting on Wed 9 June at 1500 BST (1400 GMT). Each seminar will
New preprint: Deciphering bedaquiline and clofazimine resistance in tuberculosis
Stefan Niemann, a CRyPTIC partner, led this combined experimental and modelling study looking at how resistance is conferred to bedaquline and clofazimine
New preprint: Establishing epidemiological cutoffs for the CRyPTIC UKMYC microdilution plates.
The CRyPTIC project has measured the minimum inhibitory concentrations (MICs) of 20,637 isolates to 13 different anti-TB drugs using a bespoke 96-well