New publication: Structure of MmpL3 protein
Oliver Adams, as part of his DPhil studies in Simon Newstead's group at the University of Oxford, has resolved the structure of
WHO tuberculosis mutation catalogue released
Last Friday 25 June 2021, the World Health Organization released their first report containing a catalogue of mutations in Mycobacterium tuberculosis and
Internal project seminars in June 2021
The analysis group will be presenting five consecutive seminars starting on Wed 9 June at 1500 BST (1400 GMT). Each seminar will
New preprint: Deciphering bedaquiline and clofazimine resistance in tuberculosis
Stefan Niemann, a CRyPTIC partner, led this combined experimental and modelling study looking at how resistance is conferred to bedaquline and clofazimine
New preprint: Establishing epidemiological cutoffs for the CRyPTIC UKMYC microdilution plates.
The CRyPTIC project has measured the minimum inhibitory concentrations (MICs) of 20,637 isolates to 13 different anti-TB drugs using a bespoke 96-well
BashTheBug passes 4 million classifications
A few days ago our BashTheBug volunteers passed the 4 million classifications mark! The work they are doing is key to improving
New paper: Estimating genetic adaption in 10,000 M. tuberculosis genomes
Daniel Wilson, one of the CRyPTIC partners, has recently published a paper where he introduces a new approach, genomegaMap, which estimates the
CRyPTIC inoculates its 15,000th microtitre plate
Sometime in November 2019, the 15,000th 96-well microtitre plate was inoculated with M. tuberculosis. Since each plate contains 13 different antibiotics used
Fifth Annual CRyPTIC Meeting in Hyderabad
The fifth CRyPTIC annual meeting took place in Hyderabad on Sat 26 and Sun 27 Oct 2019. Consortium partners were updated on
Paper published using machine learning to predict TB resistance
David Clifton and co-workers have recently published a paper that trained a novel machine learning model (DeepAMR) on a subset of the