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Comprehensive Resistance Prediction for Tuberculosis:
an International Consortium

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New preprint: Deciphering bedaquiline and clofazimine resistance in tuberculosis

Stefan Niemann, a CRyPTIC partner, led this combined experimental and modelling study looking at how resistance is conferred to bedaquline and clofazimine

New preprint: Establishing epidemiological cutoffs for the CRyPTIC UKMYC microdilution plates.

The CRyPTIC project has measured the minimum inhibitory concentrations (MICs) of 20,637 isolates to 13 different anti-TB drugs using a bespoke 96-well

BashTheBug passes 4 million classifications

A few days ago our BashTheBug volunteers passed the 4 million classifications mark! The work they are doing is key to improving

New paper: Estimating genetic adaption in 10,000 M. tuberculosis genomes

Daniel Wilson, one of the CRyPTIC partners, has recently published a paper where he introduces a new approach, genomegaMap, which estimates the

CRyPTIC inoculates its 15,000th microtitre plate

Sometime in November 2019, the 15,000th 96-well microtitre plate was inoculated with M. tuberculosis. Since each plate contains 13 different antibiotics used

Fifth Annual CRyPTIC Meeting in Hyderabad

The fifth CRyPTIC annual meeting took place in Hyderabad on Sat 26 and Sun 27 Oct 2019. Consortium partners were updated on

Paper published using machine learning to predict TB resistance

David Clifton and co-workers have recently published a paper that trained a novel machine learning model (DeepAMR) on a subset of the

CRyPTIC measures its 10,000th microtitre plate

The CRyPTIC Consortium measured the antibiotic susceptibility of its 10,000th sample sometime around the end of 2018. Each sample is incubated on

New paper: machine learning classifiers able to predict resistance to antituberculars

David Clifton, Yang Yang and co-workers have published a paper applying machine learning techniques to a large CRyPTIC dataset containing 13,402 isolates

Fourth Annual CRyPTIC Meeting in Dubai

The fourth annual CRyPTIC meeting took place in Dubai on 31 Oct & 1 Nov 2018 and included a meeting of the

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